
Cajun food has a reputation for bold, unapologetic flavor, and this catfish delivers every bit of that heat and depth without a single ingredient you'd need to second-guess. The homemade spice blend — smoked paprika, garlic, cayenne, oregano, and thyme — coats each fillet in a crust that turns deeply golden in a screaming-hot cast iron skillet, giving you that satisfying char you'd expect from a restaurant plate. Because everything here is built from scratch, there's no need to scan labels on pre-mixed seasonings that sometimes sneak in unexpected additives. Catfish is a naturally mild, meaty fish that soaks up bold seasoning beautifully, and the olive oil sear locks in moisture while creating a crisp exterior that holds up right through to the last bite. A squeeze of fresh lemon at the end cuts through the spice and brightens the whole dish in a way that feels effortless. It's the kind of weeknight dinner that looks and tastes like you put in way more effort than you actually did.
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In a small bowl, combine the smoked paprika, garlic powder, onion powder, dried oregano, dried thyme, black pepper, cayenne, and kosher salt. Stir until evenly mixed.
Pat the catfish fillets dry with paper towels, then sprinkle the spice blend evenly over both sides of each fillet, pressing gently so it adheres.
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