
Cajun-spiced catfish is one of those weeknight dinners that looks and tastes like you put in way more effort than you actually did. A homemade spice blend of smoked paprika, garlic powder, cayenne, and earthy dried herbs gets pressed right into the fillets before they hit a screaming-hot cast iron skillet, building a deeply golden, crackling crust that's genuinely hard to beat. The whole thing comes together with just olive oil, pantry spices, and fresh catfish — no exotic or processed ingredients in sight, which means zero stress about hidden coconut derivatives sneaking in through a marinade or sauce. Catfish is a mild, meaty fish that holds up beautifully to bold seasoning, and the high-heat sear locks in moisture while the outside gets that irresistible char. A squeeze of fresh lemon at the end cuts right through the richness and ties every bite together. Whether you're new to cooking fish or just looking for a reliable go-to, this one is straightforward enough for any skill level and impressive enough to serve to guests.
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In a small bowl, combine the smoked paprika, garlic powder, onion powder, dried oregano, dried thyme, black pepper, cayenne, and kosher salt. Stir until evenly mixed.
Pat the catfish fillets dry with paper towels, then sprinkle the spice blend evenly over both sides of each fillet, pressing gently so it adheres.
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