
Bold, smoky, and deeply satisfying, this Cajun-spiced catfish is the kind of weeknight dinner that feels like a special occasion. A homemade spice blend of smoked paprika, garlic powder, cayenne, and dried herbs does all the heavy lifting, coating each fillet in a crust that turns gloriously golden in a cast iron skillet. Many store-bought Cajun seasonings and pre-marinated fish products sneak in celery seed or celery salt, so building your own blend from scratch is the smartest move — and it honestly tastes better anyway. The technique is straightforward: get your oil shimmering hot, lay the fillets down, and resist the urge to move them until that crust forms and releases on its own. A squeeze of fresh lemon at the end cuts through the richness and brightens every bite. Whether you serve it over rice, alongside roasted vegetables, or just with a simple salad, this dish delivers serious flavor with a clean, simple ingredient list you can feel confident about.
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In a small bowl, combine the smoked paprika, garlic powder, onion powder, dried oregano, dried thyme, black pepper, cayenne, and kosher salt. Stir until evenly mixed.
Pat the catfish fillets dry with paper towels, then sprinkle the spice blend evenly over both sides of each fillet, pressing gently so it adheres.
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