
Blackened tilapia is one of those weeknight dinners that looks and tastes like it came from a serious restaurant kitchen, but comes together with pantry staples and a hot cast-iron skillet. The homemade spice blend here — smoked paprika, cumin, thyme, oregano, and a kick of cayenne — builds deep, smoky heat without a trace of ginger, which can sneak into store-bought blackening seasonings and spice blends more often than you'd expect. Mixing your own blend from scratch puts you fully in control of every ingredient on that fillet. The technique is simple but satisfying: a screaming-hot pan, a pat of butter, and a few undisturbed minutes per side to develop that gorgeous, deeply charred crust. Garlic-infused oil adds a mellow savory richness that works beautifully with the bold spices. A squeeze of lemon at the end cuts through the char and brightens the whole plate. It's bold, flaky, and completely free of the ingredient you're avoiding — no substitutions required.
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Pat the tilapia fillets completely dry with paper towels.
In a small bowl, combine the smoked paprika, dried thyme, dried oregano, ground cumin, cayenne pepper, black pepper, and salt. Stir until evenly mixed.
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